Nonlinear toxicokinetics of enrofloxacin in rats.


The dose-dependent toxicokinetics of enrofloxacin were studied by administering various single subcutaneous doses (5, 10, 20, 40, 70, 100, 150, 200, 300 and 400 mg/kg) in male Sprague-Dawley rats. The blood samples were collected from the tail veins, and the plasma concentration of enrofloxacin was determined by an HPLC-fluorescence detection (FLD) method… (More)
DOI: 10.1007/s12272-010-1118-0


Cite this paper

@article{Yi2010NonlinearTO, title={Nonlinear toxicokinetics of enrofloxacin in rats.}, author={Hee Taek Yi and Myung-Jin Shin and Soo-Min Cho and Dong-Goo Lee and Kyul Cho and Hee-Jung Cho and Soo-Jean Shin and Michael G Bartlett and Jin-Suk Kim and Ho-chul Shin}, journal={Archives of pharmacal research}, year={2010}, volume={33 11}, pages={1851-7} }