Nonlinear reduction in risk for colorectal cancer by oral contraceptive use: a meta-analysis of epidemiological studies

@article{Luan2014NonlinearRI,
  title={Nonlinear reduction in risk for colorectal cancer by oral contraceptive use: a meta-analysis of epidemiological studies},
  author={Nan-nan Luan and Lang Wu and Ting-ting Gong and Yong-Lai Wang and Bei Lin and Q. Jade Wu},
  journal={Cancer Causes & Control},
  year={2014},
  volume={26},
  pages={65-78}
}
Although the relationship between oral contraceptive (OC) use and colorectal cancer (CRC) risk has been studied extensively, the results of epidemiological studies are controversial. Therefore, we carried out a meta-analysis of epidemiological studies to summarize the available evidence and to quantify the potential dose–response relation. We searched PubMed database for studies of OC use and CRC risk that were published until the end of March 2014. Random- and fixed-effects models were applied… CONTINUE READING