Nonlinear model for capillary-tissue oxygen transport and metabolism

  title={Nonlinear model for capillary-tissue oxygen transport and metabolism},
  author={Zhijun Li and Tada Yipintsoi and James B. Bassingthwaighte},
  journal={Annals of Biomedical Engineering},
Oxygen consumption in small tissue regions cannot be measured directly, but assessment of oxygen transport and metabolism at the regional level is possible with imaging techniques using tracer15O-oxygen for positron emission tomography. On the premise that mathematical modeling of tracer kinetics is the key to the interpretation of regional concentration-time curves, an axially-distributed capillary-tissue model was developed that accounts for oxygen convection in red blood cells and plasma… CONTINUE READING


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