Nonlinear interactions in renal blood flow regulation.

  title={Nonlinear interactions in renal blood flow regulation.},
  author={Donald J. Marsh and Olga V. Sosnovtseva and Ki H. Chon and Niels-Henrik Holstein-Rathlou},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  volume={288 5},
We have developed a model of tubuloglomerular feedback (TGF) and the myogenic mechanism in afferent arterioles to understand how the two mechanisms are coupled. This paper presents the model. The tubular model predicts pressure, flow, and NaCl concentration as functions of time and tubular length in a compliant tubule that reabsorbs NaCl and water; boundary conditions are glomerular filtration rate (GFR), a nonlinear outflow resistance, and initial NaCl concentration. The glomerular model… CONTINUE READING
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