Noninvasive technique for measurement of heartbeat regularity in zebrafish (Danio rerio) embryos

  title={Noninvasive technique for measurement of heartbeat regularity in zebrafish (Danio rerio) embryos},
  author={Po K. Chan and Chun Chi Lin and Shuk Han Cheng},
  journal={BMC Biotechnology},
  pages={11 - 11}
BackgroundZebrafish (Danio rerio), due to its optical accessibility and similarity to human, has emerged as model organism for cardiac research. Although various methods have been developed to assess cardiac functions in zebrafish embryos, there lacks a method to assess heartbeat regularity in blood vessels. Heartbeat regularity is an important parameter for cardiac function and is associated with cardiotoxicity in human being. Using stereomicroscope and digital video camera, we have developed… 

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