Noninvasive scoring systems in patients with nonalcoholic fatty liver disease with normal alanine aminotransferase levels

@article{Yoneda2012NoninvasiveSS,
  title={Noninvasive scoring systems in patients with nonalcoholic fatty liver disease with normal alanine aminotransferase levels},
  author={Masato Yoneda and Kento Imajo and Yuichiro Eguchi and Hideki Fujii and Yoshio Sumida and Hideyuki Hyogo and Masafumi Ono and Yasuaki Suzuki and Takumi Kawaguchi and Noriaki Aoki and Michio Sata and Kazuyuki Kanemasa and Yutaka Kohgo and Toshiji Saibara and Kazuaki Chayama and Yoshito Itoh and Toshikazu Yoshikawa and Keizo Anzai and Kazuma Fujimoto and Takeshi Okanoue and Atsushi Nakajima},
  journal={Journal of Gastroenterology},
  year={2012},
  volume={48},
  pages={1051-1060}
}
The severity of liver fibrosis must be estimated to determine the prognosis, for surveillance, and for optimal treatment of nonalcoholic fatty liver disease (NAFLD). However, the severity of hepatic fibrosis tends to be underestimated in patients with normal ALT. We investigated histological data and scoring systems (FIB-4 index, NAFLD fibrosis score, BARD score, and AST/ALT ratio) of 1,102 liver-biopsy-confirmed NAFLD patients. A total of 235 NAFLD patients with normal ALT were estimated to… CONTINUE READING

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