Noninvasive regional cerebral blood flow measurements in dementia.

  title={Noninvasive regional cerebral blood flow measurements in dementia.},
  author={Fumio Yamaguchi and John Stirling Meyer and Mitsutoshi Yamamoto and Fumihiko Sakai and Theresa Shaw},
  journal={Archives of neurology},
  volume={37 7},
Regional cerebral blood flow measured in patients with dementias (N = 60) using xenon Xe 133 inhalation was compared with measurements in health volunteers (N = 70). Volunteers were age-matched (N = 15); another group was younger. In normal aging, there is progressive, diffuse reduction of weight and flow of gray matter (F1) but not of white matter. Therefore, age-matched control subjects are necessary in studies of dementia. In Alzheimer's disease (AD), F1 shows bilateral and symmetrical… CONTINUE READING
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