Noninvasive quantification of the cerebral metabolic rate for glucose using positron emission tomography, 18F-fluoro-2-deoxyglucose, the Patlak method, and an image-derived input function.

@article{Chen1998NoninvasiveQO,
  title={Noninvasive quantification of the cerebral metabolic rate for glucose using positron emission tomography, 18F-fluoro-2-deoxyglucose, the Patlak method, and an image-derived input function.},
  author={Kewei W Chen and D. E. Bandy and Eric Reiman and Sung-cheng Huang and Marcus E Lawson and Dingan Feng and Lang Sheng Yun and Anita Palant},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={1998},
  volume={18 7},
  pages={716-23}
}
The authors developed and tested a method for the noninvasive quantification of the cerebral metabolic rate for glucose (CMRglc) using positron emission tomography (PET), 18F-fluoro-2-deoxyglucose, the Patlak method, and an image-derived input function. Dynamic PET data acquired 12 to 48 seconds after rapid tracer injection were summed to identify carotid artery regions of interest (ROIs). The input function then was generated from the carotid artery ROIs. To correct spillover, the early summed… CONTINUE READING
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Methods for the correction of vascular artifacts in PET 0 - 15 water brain mapping studies

  • K Chen, E Reiman, M Lawson, LS Yun, 0 Bandy, A Palant
  • IEEE Nuclear Sciences
  • 1995

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