Noninvasive prenatal diagnosis: current practice and future perspectives

  title={Noninvasive prenatal diagnosis: current practice and future perspectives},
  author={S. Hahn and L. Chitty},
  journal={Current Opinion in Obstetrics and Gynecology},
  • S. Hahn, L. Chitty
  • Published 2008
  • Medicine
  • Current Opinion in Obstetrics and Gynecology
  • Purpose of review To review recent developments in the noninvasive determination of fetal genetic loci via the use of fetal cells or cell-free nucleic acids in maternal blood, and provide an overview of the possibilities for future clinical applications. Recent findings Noninvasive prenatal fetal sex or Rhesus D status determination via the analysis of cell-free fetal DNA is now offered by a number of European centres. The detection of fetal loci not completely disparate from maternal ones… CONTINUE READING
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