Noninvasive positive pressure ventilation in subjects with stable COPD: a randomized trial

  title={Noninvasive positive pressure ventilation in subjects with stable COPD: a randomized trial},
  author={Surya P Bhatt and Michael W. Peterson and Jeffrey S. Wilson and Lakshmi Durairaj},
  booktitle={International journal of chronic obstructive pulmonary disease},
BACKGROUND The use of domiciliary noninvasive positive pressure ventilation (NPPV) in stable chronic obstructive pulmonary disease (COPD) with chronic hypercapnic respiratory failure has yielded variable effects on survival, quality of life, and dyspnea. We hypothesized that use of NPPV in stable COPD and partial pressure of carbon dioxide (PaCO2) <52 mmHg might result in improvement in quality of life and dyspnea. METHODS Thirty patients with stable COPD (forced expiratory volume in the… CONTINUE READING
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