Noninvasive oxygen partial pressure measurement of human body fluids in vivo using magnetic resonance imaging.

@article{Zaharchuk2006NoninvasiveOP,
  title={Noninvasive oxygen partial pressure measurement of human body fluids in vivo using magnetic resonance imaging.},
  author={Greg Zaharchuk and Reed F. Busse and Guy Rosenthal and Geoffery T Manley and Orit A. Glenn and W P Dillon},
  journal={Academic radiology},
  year={2006},
  volume={13 8},
  pages={1016-24}
}
RATIONALE AND OBJECTIVES The oxygen partial pressure (pO2) of human body fluids reflects the oxygenation status of surrounding tissues. All existing fluid pO2 measurements are invasive, requiring either microelectrode/optode placement or fluid removal. The purpose of this study is to develop a noninvasive magnetic resonance imaging method to measure the pO2 of human body fluids. MATERIALS AND METHODS We developed an imaging paradigm that exploits the paramagnetism of molecular oxygen to… CONTINUE READING
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