Noninvasive measurement of the tension-time index in children with neuromuscular disease.

@article{Mulreany2003NoninvasiveMO,
  title={Noninvasive measurement of the tension-time index in children with neuromuscular disease.},
  author={Laura T Mulreany and Daniel J Weiner and Joseph M. McDonough and Howard B Panitch and Julian Allen},
  journal={Journal of applied physiology},
  year={2003},
  volume={95 3},
  pages={931-7}
}
Respiratory muscle weakness is common in children with neuromuscular disease (NMD). We hypothesized that weakness puts them at risk for respiratory muscle fatigue, a harbinger of chronic respiratory failure. We therefore measured a noninvasive index of respiratory muscle fatigue, the tension-time index of the respiratory muscles (TT(mus)), in 11 children with NMD and 13 control subjects. Spirometric flow rates and maximal inspiratory pressure were significantly lower in the NMD group than in… CONTINUE READING
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Non-invasive assessment of respiratory muscle fatigue during inspiratory loading (Abstract)

  • L Mulreany, DJ Weiner, JM McDonough, HB Panitch, JL. Allen
  • Am J Respir Crit Care Med 165:
  • 2002
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Below FRC ventilation: augmented breaths by passive outward chest wall recoil (Abstract)

  • D Rifkin, JM McDonough, HB Panitch, JL. Allen
  • Am J Respir Crit Care Med 161:
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