Noninvasive measurement of liver iron concentration at MRI in children with acute leukemia: initial results

@article{Vag2011NoninvasiveMO,
  title={Noninvasive measurement of liver iron concentration at MRI in children with acute leukemia: initial results},
  author={Tibor Vag and Karim Kentouche and Ines Krumbein and J{\"u}rgen R. Reichenbach and Eric C Lopatta and Diane M. Renz and Martin Stenzel and James Beck and Werner A. Kaiser and Hans-Joachim Mentzel},
  journal={Pediatric Radiology},
  year={2011},
  volume={41},
  pages={980-984}
}
Routine assessment of body iron load in patients with acute leukemia is usually done by serum ferritin (SF) assay; however, its sensitivity is impaired by different conditions including inflammation and malignancy. To estimate, using MRI, the extent of liver iron overload in children with acute leukemia and receiving blood transfusions, and to examine the association between the degree of hepatic iron overload and clinical parameters including SF and the transfusion iron load (TIL). A total of… CONTINUE READING
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