Noninvasive measurement of cardiovascular function in mice with high-temporal-resolution small-animal PET.

@article{Kreissl2006NoninvasiveMO,
  title={Noninvasive measurement of cardiovascular function in mice with high-temporal-resolution small-animal PET.},
  author={Michael C. Kreissl and Hsiao-Ming Wu and David B. Stout and Waldemar Ladno and Thomas Hellmut Schindler and Xiaoli Zhang and John O. Prior and Mayumi L Prins and Arion Chatziioannou and Sung-Cheng Huang and Heinrich R. Schelbert},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2006},
  volume={47 6},
  pages={974-80}
}
UNLABELLED The aim of this study was to explore the feasibility of determining parameters of cardiovascular function in mice noninvasively by high-temporal-resolution imaging with a dedicated small-animal PET system. METHODS Twenty-five anesthetized mice (28.8 +/- 4.6 g) were injected via an intravenous catheter with a 30-microL bolus of (18)F-FDG (8-44 MBq). The first 9 s of data were reconstructed into 30 frames of 0.3 s using filtered backprojection. The time-activity curve derived from a… CONTINUE READING