Noninvasive measurement of anatomic structure and intraluminal oxygenation in the gastrointestinal tract of living mice with spatial and spectral EPR imaging.

@article{He1999NoninvasiveMO,
  title={Noninvasive measurement of anatomic structure and intraluminal oxygenation in the gastrointestinal tract of living mice with spatial and spectral EPR imaging.},
  author={Guanglong He and Ravi A. Shankar and Michael Chzhan and Alexandre Samouilov and Periannan Kuppusamy and Jay L. Zweier},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1999},
  volume={96 8},
  pages={4586-91}
}
EPR imaging has emerged as an important tool for noninvasive three-dimensional (3D) spatial mapping of free radicals in biological tissues. Spectral-spatial EPR imaging enables mapping of the spectral information at each spatial position, and, from the observed line width, the localized tissue oxygenation can be mapped. We report the development of EPR imaging instrumentation enabling 3D spatial and spectral-spatial EPR imaging of small animals. This instrumentation, along with the use of a… CONTINUE READING
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