Noninvasive in vivo tomographic optical imaging of cellular morphology in the breast: possible convergence of microscopic pathology and macroscopic radiology.

@article{Li2008NoninvasiveIV,
  title={Noninvasive in vivo tomographic optical imaging of cellular morphology in the breast: possible convergence of microscopic pathology and macroscopic radiology.},
  author={Changqing Li and Stephen R Grobmyer and Nicole Massol and Xiaoping Liang and Qizhi Zhang and Lin Chen and Laurie Lee Fajardo and Huabei Jiang},
  journal={Medical physics},
  year={2008},
  volume={35 6},
  pages={
          2493-501
        }
}
This article presents a pilot study of multispectral diffuse optical tomography for noninvasively imaging volume fraction and mean size of cellular scattering components in the breast. Cellular morphology images for a total of 14 cases (four malignant breast and ten benign lesions) were obtained. Analyzing the images based on the pathological findings of the cases studied, we found that light scattering in the breast was contributed from both the nucleus and organelles such as mitochondria and… CONTINUE READING
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