Noninvasive imaging by optical coherence tomography to monitor retinal degeneration in the mouse.

  title={Noninvasive imaging by optical coherence tomography to monitor retinal degeneration in the mouse.},
  author={Qianjun Li and Adrian M. Timmers and Kathy Hunter and C{\'e}sar Gonz{\'a}lez-Pola and Alfred S Lewin and David H. Reitze and William W. Hauswirth},
  journal={Investigative ophthalmology & visual science},
  volume={42 12},
PURPOSE Optical coherence tomography (OCT) is a high-resolution imaging technique that measures the intensity of backscattered light from biological microstructures in living tissue. The objective was to evaluate OCT as a routine, noninvasive technique for quantitative measurements of retinal thickness and detachment in small animal models of retinal degenerative diseases. METHODS An OCT scanning unit was designed and built to visualize retinal tissue from rodents at high resolution in vivo… CONTINUE READING
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Spectral domain optical coherence tomography in mouse models of retinal degeneration.

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