Noninvasive assessment of myocardial viability in a small animal model: comparison of MRI, SPECT, and PET.

@article{Thomas2008NoninvasiveAO,
  title={Noninvasive assessment of myocardial viability in a small animal model: comparison of MRI, SPECT, and PET.},
  author={Daniel E. Thomas and Harshali S Bal and Jeffrey S. Arkles and James M. Horowitz and Luis Araujo and Paul D. Acton and Victor A. Ferrari},
  journal={Magnetic resonance in medicine},
  year={2008},
  volume={59 2},
  pages={252-9}
}
Acute myocardial infarction (AMI) research relies increasingly on small animal models and noninvasive imaging methods such as MRI, single-photon emission computed tomography (SPECT), and positron emission tomography (PET). However, a direct comparison among these techniques for characterization of perfusion, viability, and infarct size is lacking. Rats were studied within 18-24 hr post AMI by MRI (4.7 T) and subsequently (40-48 hr post AMI) by SPECT ((99)Tc-MIBI) and micro-PET ((18)FDG). A… CONTINUE READING

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