Noninvasive assessment of murine pulmonary arterial pressure: validation and application to models of pulmonary hypertension.

@article{Thibault2010NoninvasiveAO,
  title={Noninvasive assessment of murine pulmonary arterial pressure: validation and application to models of pulmonary hypertension.},
  author={H{\'e}l{\`e}ne B Thibault and Baptiste Kurtz and Michael J. Raher and Rahamthulla S. Shaik and Aaron B Waxman and Genevi{\`e}ve Anne Derumeaux and Elkan F. Halpern and Kenneth D. Bloch and Marielle Scherrer-Crosbie},
  journal={Circulation. Cardiovascular imaging},
  year={2010},
  volume={3 2},
  pages={157-63}
}
BACKGROUND Genetically modified mice offer the unique opportunity to gain insight into the pathophysiology of pulmonary arterial hypertension. In mice, right heart catheterization is the only available technique to measure right ventricular systolic pressure (RVSP). However, it is a terminal procedure and does not allow for serial measurements. Our objective was to validate a noninvasive technique to assess RVSP in mice. METHODS AND RESULTS Right ventricle catheterization and echocardiography… CONTINUE READING