Noninvasive assessment of cerebral oxygenation during acclimation to hypobaric hypoxia.

  title={Noninvasive assessment of cerebral oxygenation during acclimation to hypobaric hypoxia.},
  author={Jeff F. Dunn and Oleg Y. Grinberg and Marcie A Roche and Casmiar I Nwaigwe and Huagang G Hou and Harold M. Swartz},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  volume={20 12},
Factors regulating cerebral tissue PO2 (PtO2) are complex. With the increased use of clinical PtO2 monitors, it has become important to elucidate these mechanisms. The authors are investigating a new methodology (electron paramagnetic resonance oximetry) for use in monitoring cerebral PtO2 in awake animals over time courses of weeks. The authors used this to study cerebral PtO2 in rats during chronic acclimation to hypoxia predicting that such acclimation would cause an increase in PtO2 because… CONTINUE READING
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