Noninvasive Prenatal Testing - When Is It Advantageous to Apply

  title={Noninvasive Prenatal Testing - When Is It Advantageous to Apply},
  author={Thomas Liehr and Angela Lauten and Uwe Schneider and Ekkehard Schleu{\ss}ner and Anja Weise},
  journal={Biomedicine Hub},
  pages={1 - 11}
Nowadays it is common sense in obstetrics that an increased risk for pregnancy loss due to invasive testing does not exist. Nonetheless, noninvasive prenatal testing (NIPT) is a hot topic, even though this approach does not provide a reduction of unintentionally induced abortions. NIPT has a number of shortcuts which are highlighted in this review, including: (1) in NIPT placental rather than fetal DNA is studied, (2) NIPT fails in 2-6% of cases, and (3) trisomy 21 accounts for only ∼50% of… 

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