Noninvasive In vivo Analysis of Human Small Intestinal Paracellular Absorption: Regulation by Na+-Glucose Cotransport

@article{Turner2004NoninvasiveIV,
  title={Noninvasive In vivo Analysis of Human Small Intestinal Paracellular Absorption: Regulation by Na+-Glucose Cotransport},
  author={J. R. Turner and D. Cohen and R. Mrsny and J. Madara},
  journal={Digestive Diseases and Sciences},
  year={2004},
  volume={45},
  pages={2122-2126}
}
Activation of intestinal Na+–glucose cotransport increases paracellular movement of inert tracers in cultured monolayers, isolated rodent intestinal mucosae, and in rodents in vivo. However, not all studies have demonstrated comparable effects on human intestinal paracellular absorption. We sought to assess the effects of Na+–glucose cotransport on paracellular absorption in human beings using a simple noninvasive assay. Study subjects drank six 200-ml doses of test solution, composed of 0.8% w… Expand
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  • Matthew A. Odenwald, J. Turner
  • Medicine
  • Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • 2013
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