Nonidentical intracellular drug release rates in Raman and fluorescence spectroscopic determination.

Abstract

Intracellular drug release rates were measured by monitoring mitoxantrone (MTX) on gold nanoparticle (AuNP) carriers by means of real-time label-free bimodal imaging with confocal Raman and fluorescence spectroscopy. The quenching nature of the MTX-AuNPs by nanometal surface energy transfer (NSET) was analyzed using the determined Stern-Volmer constant of… (More)
DOI: 10.1039/c4cp04235b

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