Nonidentical intracellular drug release rates in Raman and fluorescence spectroscopic determination.


Intracellular drug release rates were measured by monitoring mitoxantrone (MTX) on gold nanoparticle (AuNP) carriers by means of real-time label-free bimodal imaging with confocal Raman and fluorescence spectroscopy. The quenching nature of the MTX-AuNPs by nanometal surface energy transfer (NSET) was analyzed using the determined Stern-Volmer constant of… (More)
DOI: 10.1039/c4cp04235b


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