Nonhuman primate model of schizophrenia using a noninvasive EEG method.

@article{GildaCosta2013NonhumanPM,
  title={Nonhuman primate model of schizophrenia using a noninvasive EEG method.},
  author={Ricardo Gil-da-Costa and Gene R. Stoner and Raynard Fung and T. D. Albright},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2013},
  volume={110 38},
  pages={15425-30}
}
There is growing evidence that impaired sensory-processing significantly contributes to the cognitive deficits found in schizophrenia. For example, the mismatch negativity (MMN) and P3a event-related potentials (ERPs), neurophysiological indices of sensory and cognitive function, are reduced in schizophrenia patients and may be used as biomarkers of the disease. In agreement with glutamatergic theories of schizophrenia, NMDA antagonists, such as ketamine, elicit many symptoms of schizophrenia… CONTINUE READING