Nonhormonal management of menopause-associated vasomotor symptoms: 2015 position statement of The North American Menopause Society

@article{Carpenter2015NonhormonalMO,
  title={Nonhormonal management of menopause-associated vasomotor symptoms: 2015 position statement of The North American Menopause Society},
  author={Janet S. Carpenter and Margery L. S. Gass and Pauline M. Maki and Katherine M. Newton and JoAnn V. Pinkerton and Maida Taylor and Wulf. H. Utian and P F Schnatz and Andrew M. Kaunitz and Marla Shapiro and Jan Leslie Shifren and Howard N. Hodis and Sheryl A Kingsberg and James H. Liu and Gloria Richard-Davis and Nanette F Santoro and Lynnette Leidy Sievert and Isaac Schiff and Caitlin A. Pike},
  journal={Menopause},
  year={2015},
  volume={22},
  pages={1155–1174}
}
Objective:To update and expand The North American Menopause Society's evidence-based position on nonhormonal management of menopause-associated vasomotor symptoms (VMS), previously a portion of the position statement on the management of VMS. Methods:NAMS enlisted clinical and research experts in the field and a reference librarian to identify and review available evidence. Five different electronic search engines were used to cull relevant literature. Using the literature, experts created a… 

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References

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No evidence is found from randomised controlled trials on whether exercise is an effective treatment relative to other interventions or no intervention in reducing hot flushes and or night sweats in symptomatic women.

Therapeutic decisions for menopause: results of the DAMES project in central Massachusetts

This study documents a relatively heavy burden of symptoms in a relatively healthy population and provides an update on earlier studies in Massachusetts.

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The preliminary evidence warrants clinicians discussing the potential of S-equol for the alleviation of VMS with patients, and subanalysis of epidemiologic studies suggests that equol producers are more likely to benefit from soyfood consumption than nonproducers with respect to both cardiovascular disease and osteoporosis, although the data are inconsistent.

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Although individual trials suggest benefits from certain therapies, data are insufficient to support the effectiveness of any complementary and alternative therapy in this review for the management of menopausal symptoms.

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The SSRIs or SNRIs, clonidine, and gabapentin trials provide evidence for efficacy; however, effects are less than for estrogen, few trials have been published and most have methodological deficiencies, generalizability is limited, and adverse effects and cost may restrict use for many women.

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