Nongenetic inheritance and transgenerational epigenetics.

  title={Nongenetic inheritance and transgenerational epigenetics.},
  author={Moshe Szyf},
  journal={Trends in molecular medicine},
  volume={21 2},
The idea that inherited genotypes define phenotypes has been paramount in modern biology. The question remains, however, whether stable phenotypes could be also inherited from parents independently of the genetic sequence per se. Recent data suggest that parental experiences can be transmitted behaviorally, through in utero exposure of the developing fetus to the maternal environment, or through either the male or female germline. The challenge is to delineate a plausible mechanism. In the past… CONTINUE READING
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