Nongenetic causes of childhood cancers: evidence from international variation, time trends, and risk factor studies.

@article{Bunin2004NongeneticCO,
  title={Nongenetic causes of childhood cancers: evidence from international variation, time trends, and risk factor studies.},
  author={Greta R. Bunin},
  journal={Toxicology and applied pharmacology},
  year={2004},
  volume={199 2},
  pages={91-103}
}
Ionizing radiation and a variety of genetic conditions are thought to explain 5-10% of childhood cancers. Infection with Epstein-Barr virus (EBV) in parts of Africa and human immunodeficiency virus (HIV) increase the risk of Burkitt's lymphoma and Kaposi's sarcoma, respectively. Other risk factors have not been conclusively identified. A review of the data on international variation in incidence, recent changes in incidence, and risk factors suggests that many childhood cancers are likely to… CONTINUE READING

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