Nonfunctioning islet cell tumors of the pancreas: a difficult diagnosis but one worth the effort.

@article{Madura1997NonfunctioningIC,
  title={Nonfunctioning islet cell tumors of the pancreas: a difficult diagnosis but one worth the effort.},
  author={James A. Madura and O William Cummings and Eric A. Wiebke and Thomas A. Broadie and R L Goulet and Thomas J. Howard},
  journal={The American surgeon},
  year={1997},
  volume={63 7},
  pages={573-7; discussion 577-8}
}
Islet cell tumors of the pancreas usually secrete gastroenteropancreatic peptides causing well-recognized clinical syndromes. Description of these syndromes and the identification of the responsible hormones by radioimmunoassay has led to a better understanding of neuroendocrine regulatory function. More recently, similar tumors have been seen that contain various peptides on immunohistochemical stain but do not secrete these substances sufficiently to cause clinical symptoms. Nonetheless, they… CONTINUE READING

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