Nonfibrinolytic functions of plasminogen.

  title={Nonfibrinolytic functions of plasminogen.},
  author={Victoria A. Ploplis and Francis J. Castellino},
  volume={21 2},
Although the roles of plasminogen and plasmin in mediating blood clot dissolution are well known, the availability of mice deficient for components of the fibrinolytic system has allowed direct approaches to be made toward elucidating the role of these proteins in other diverse physiological and pathophysiological processes. A number of these studies have identified plasminogen as playing an important role in inflammation and other cell migratory processes. With the identification of receptors… CONTINUE READING