Nonessential amino acids and glutamine decrease the time of the first three cleavage divisions and increase compaction of mouse zygotes in vitro

@article{Lane1997NonessentialAA,
  title={Nonessential amino acids and glutamine decrease the time of the first three cleavage divisions and increase compaction of mouse zygotes in vitro},
  author={Michelle T Lane and David K Gardner},
  journal={Journal of Assisted Reproduction and Genetics},
  year={1997},
  volume={14},
  pages={398-403}
}
Purpose: The objective of this study was to determine the effect of supplementing embryo culture media with amino acids on the duration of the first three cell cycles of mouse zygotes in vitro. Methods: Zygotes were cultured in the presence of different groups of amino acids and cleavage assessed every 30 min. Results: Culture of zygotes with Eagle’s nonessential amino acids and glutamine significantly reduced the time of cleavage divisions to the eight-cell stage compared to culture without… CONTINUE READING

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