Nonequilibrium sensing and its analogy to kinetic proofreading

  title={Nonequilibrium sensing and its analogy to kinetic proofreading},
  author={David Hartich and A. C. Barato and U. Seifert},
For a paradigmatic model of chemotaxis, we analyze the effect how a nonzero affinity driving receptors out of equilibrium affects sensitivity. This affinity arises whenever changes in receptor activity involve ATP hydrolysis. The sensitivity integrated over a ligand concentration range is shown to be enhanced by the affinity, providing a measure of how much energy consumption improves sensing. With this integrated sensitivity we can establish an intriguing analogy between sensing with… CONTINUE READING
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Information-theoretic versus thermodynamic entropy production in autonomous sensory networks

  • A. C. Barato, D. Hartich, U. Seifert
  • Phys. Rev. E 87 (2013) 042104.
  • 2013
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