Nonenzymic, polyvalent anion-catalyzed formation of methylglyoxal as an explanation of its presence in physiological systems.

Abstract

The long standing question of the source of methylglyoxal formed in glycolyzing tissues was considered. Nonbiological studies, made with chemical model systems, made evident that the formation of methylglyoxal from dihydroxyacetone and from Dr.-glyceraldehyde under physiological conditions of pH and temperature is catalyzed by Tris and by certain polyvalent… (More)

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@article{Riddle1968NonenzymicPA, title={Nonenzymic, polyvalent anion-catalyzed formation of methylglyoxal as an explanation of its presence in physiological systems.}, author={V M Riddle and Frederick Lorenz}, journal={The Journal of biological chemistry}, year={1968}, volume={243 10}, pages={2718-24} }