Nonencapsulated Streptococcus pneumoniae as a cause of chronic adenoiditis

  title={Nonencapsulated Streptococcus pneumoniae as a cause of chronic adenoiditis},
  author={Cheshil Dixit and Lance E. Keller and Jessica L. Bradshaw and Daphn{\'e} A. Robinson and Edwin J Swiatlo and Larry S McDaniel},
Streptococcus pneumoniae is an important human pathogen. To cause disease, it must first colonize the nasopharynx. The widespread use of pneumococcal-conjugate vaccines which target the capsular polysaccharide has led to decreased nasopharyngeal carriage of vaccine serotypes, but a concomitant increase in carriage of non-vaccine serotypes and nonencapsulated S. pneumoniae (NESp). Some NESp express pneumococcal surface protein K (PspK), a virulence factor shown to contribute to nasopharyngeal… CONTINUE READING
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