Noncoding control region of naturally occurring BK virus variants: Sequence comparison and functional analysis

@article{Moens1995NoncodingCR,
  title={Noncoding control region of naturally occurring BK virus variants: Sequence comparison and functional analysis},
  author={Ugo Moens and Terje Johansen and John Inge Johnsen and Ole Morten Seternes and Terje Ingemar Traavik},
  journal={Virus Genes},
  year={1995},
  volume={10},
  pages={261-275}
}
The human polyomavirus BK (BKV) has a proven oncogenic potential, but its contribution to tumorigenesis under natural conditions remains undetermined. As for other primate polyomaviruses, the approximately 5.2 kbp double-stranded circular genome of BKV has three functional regions: the coding regions for the two early (T, t antigens) and four late (agno, capsid proteins; VP1-3) genes separated by a noncoding control region (NCCR). The NCCR contains the origin of replication as well as a… CONTINUE READING
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