Noncoding RNA and Polycomb recruitment.

  title={Noncoding RNA and Polycomb recruitment.},
  author={Neil Brockdorff},
  volume={19 4},
A plethora of noncoding (nc) RNAs has been revealed through the application of high-throughput analysis of the transcriptome, and this has led to an intensive search for possible biological functions attributable to these transcripts. A major category of functional ncRNAs that has emerged is for those that are implicated in coordinate gene silencing, either in cis or in trans. The archetype for this class is the well-studied long ncRNA Xist which functions in cis to bring about transcriptional… CONTINUE READING
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