Nonclassical Aspects of Differential Vitamin D Receptor Activation

  title={Nonclassical Aspects of Differential Vitamin D Receptor Activation},
  author={Professor Dennis Andress},
The ‘classical’ effects of vitamin D receptor activator or agonist (VDRA) therapy for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease primarily involves suppressive effects on the parathyroid gland, and regulation of calcium and phosphorus absorption in the intestine and mobilisation in bone. Observational studies in haemodialysis patients report improved cardiovascular and all-cause survival among those receiving VDRA therapy compared with those not on… CONTINUE READING


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