Noncardiac Chest Pain: Epidemiology, Natural Course and Pathogenesis

  title={Noncardiac Chest Pain: Epidemiology, Natural Course and Pathogenesis},
  author={Ronnie Fass and Sami Ren{\'e} Achem},
  booktitle={Journal of neurogastroenterology and motility},
Noncardiac chest pain is defined as recurrent chest pain that is indistinguishable from ischemic heart pain after a reasonable workup has excluded a cardiac cause. Noncardiac chest pain is a prevalent disorder resulting in high healthcare utilization and significant work absenteeism. However, despite its chronic nature, noncardiac chest pain has no impact on patients' mortality. The main underlying mechanisms include gastroesophageal reflux, esophageal dysmotility and esophageal… CONTINUE READING


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