Nonadherent cell population of human marrow culture is a complementary source of mesenchymal stem cells (MSCs)

@article{Wan2006NonadherentCP,
  title={Nonadherent cell population of human marrow culture is a complementary source of mesenchymal stem cells (MSCs)},
  author={Chao Wan and Qiling He and Mervyn McCaigue and David R Marsh and Gang Li},
  journal={Journal of Orthopaedic Research},
  year={2006},
  volume={24}
}
To obtain enough quantity of osteogenic cells is a challenge for successful cell therapy in bone defect treatment, and cell numbers were usually achieved by culturing bone marrow cells in a relatively long duration. This study reports a simple and cost‐effective method to enhance the number of mesenchymal stem cells (MSCs) by collecting and replating the nonadherent cell population of marrow MSCs culture. Bone marrow MSCs were isolated from 11 patients, cultured at a density of 1 × 105/cm2 to 1… Expand
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