Nonadherence is associated with late rejection in pediatric heart transplant recipients.

  title={Nonadherence is associated with late rejection in pediatric heart transplant recipients.},
  author={Jeremy M Ringewald and Samuel S. Gidding and Susan E Crawford and Carl Lewis Backer and Constantine Mavroudis and Elfriede Pahl},
  journal={The Journal of pediatrics},
  volume={139 1},
OBJECTIVES The objective was to study the impact of nonadherence on late rejection after pediatric heart transplantation. STUDY DESIGN This was a retrospective cohort study of cardiac transplant recipients surviving >6 months (n = 50). Patients were stratified by episodes of late rejection. End points were defined by cyclosporin A (CSA) level, CSA level variability, and patient admission of nonadherence. RESULTS In 15 patients there were 49 episodes of late rejection, and 37 (76%) were… CONTINUE READING


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