Nonadherence in patients with breast cancer receiving oral therapies.

@article{Moore2010NonadherenceIP,
  title={Nonadherence in patients with breast cancer receiving oral therapies.},
  author={Susan Moore},
  journal={Clinical journal of oncology nursing},
  year={2010},
  volume={14 1},
  pages={
          41-7
        }
}
  • S. Moore
  • Published 29 January 2010
  • Medicine
  • Clinical journal of oncology nursing
Adherence is a potentially significant issue in oral therapy for breast cancer. Suboptimal adherence to medication regimens impacts clinical benefit and can result in treatment resistance, disease progression, and even death. Nonadherence is a greater issue with oral medications because the majority of responsibility shifts from healthcare professionals to the patient. Improving adherence to medication regimens can impact patients' likelihood of successful clinical outcomes. Many factors… 
View on PubMed
cjon.ons.org
37 Citations
Highly Influential Citations
3
Background Citations
17
Methods Citations
3

37 Citations

Citation Type

Citation Type

A review on adherence management in patients on oral cancer therapies.
  • L. Wood
  • Medicine
    European journal of oncology nursing : the official journal of European Oncology Nursing Society
  • 2012
Adherence and oral agents with older patients.
Influencing Factors on Medication Adherence in Colorectal Cancer Patients Receiving Oral Chemotherapy
TLDR
It is important to develop nursing intervention for medication adherence in colorectal cancer patients that focus on symptom experience and to consider about perceived health status and combination of IV chemotherapy.
Impact of pharmacy channel on adherence to oral oncolytics
TLDR
Pharmacy channel may be influential on abandonment and adherence in patients filling prescriptions in traditional retail (TR) versus specialty pharmacy (SP) channels and lower rates of abandonment and higher rates of adherence were observed among SP patients versus TR.
Oral Chemotherapy, A Tough Pill To Swallow: A Systematic Review
TLDR
As patients begin to receive more oral chemotherapies in the place of the traditional parenteral therapies, the responsibility for treatment falls on the shoulders of patients and their caregivers, which places patients at risk for medications errors.
Adherence to Oral Administration of Endocrine Treatment in Patients With Breast Cancer: A Qualitative Study
TLDR
This study shows that adherence assumes different connotations that are mainly influenced by the type of relationship established with health professionals the attention paid to the person, the information received, and the influence that the drug has on the disease.
Adherence and discontinuation of oral hormonal therapy in patients with hormone receptor positive breast cancer
TLDR
A great diversity among rates of adherence and/or discontinuation of hormonal therapy for breast cancer is observed, suggesting the need for patient continuous education and a pharmacotherapeutic follow up by health professionals to improve these clinical outcomes.
Influence of patient and treatment factors on adherence to adjuvant endocrine therapy in breast cancer.
TLDR
Women with breast cancer may be at risk for nonadherence to prescribed endocrine therapy if they experience depression or anxiety and symptoms prior to initiating therapy, and oncology nurses should be alert to women who are depressed or anxious or who are experiencing symptoms.
Oral anticancer agent medication adherence by outpatients
TLDR
Overall, the medication compliance of the patients taking the oral anticancer agents was good, but the medication adherence was insufficient, and a better understanding of the effectiveness and necessity of drugs and their side-effects is required.
Determinants and associated factors influencing medication adherence and persistence to oral anticancer drugs: a systematic review.
...
1
2
3
4
...

References

SHOWING 1-10 OF 65 REFERENCES
Adherence to oral endocrine therapy for breast cancer: a nursing perspective.
TLDR
The issues surrounding adherence, paying specific attention to adjuvant endocrine therapy for breast cancer, and strategies to reduce nonadherence that nurses can incorporate into clinical practice are summarized.
Patient adherence and persistence with oral anticancer treatment
TLDR
Adherence and persistence rates ranged from 16% to 100% with different therapies and different methods of measurement, and studies that included educational, behavioral, and multidimensional interventions to improve adherence were described.
Insight into barriers against optimal adherence to oral hormonal therapy in women with breast cancer.
TLDR
It is suggested that treatment adherence could be improved if healthcare professionals discuss and emphasize the importance of taking oral medications as directed and the effect of adherence on clinical outcomes.
Challenges for improving medication adherence.
TLDR
The results of a pharmacy care program designed to improve medication adherence for patients with multiple chronic medical conditions, including hypertension and elevated cholesterol levels are reported, focusing on elderly patients who were taking multiple medications and therefore were at risk for poor adherence.
Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection
TLDR
Given the critical importance of adherence to therapy to patient outcome, secondary prevention of HIV infection, and willingness of providers to prescribe therapy, this prospectively investigated the association between protease inhibitor adherence and patient outcome and factors related to adherence.
Patient noncompliance with self‐administered chemotherapy
TLDR
Patients with breast cancer enrolled in protocols that included the orally administered medications Cytoxan and/or prednisone were interviewed and assessed at five points in time over a 6‐month period, showing more nonadherence in the clinic and private community settings than in the academic setting.
Assessing Medication Adherence in the Elderly
TLDR
The most practical method of medication adherence assessment for most elderly patients may be through patient or caregiver interview using open-ended, nonthreatening and nonjudgmental questions.
Facilitating Oral Chemotherapy Treatment and Compliance Through Patient/Family-Focused Education
TLDR
An overview of the current status of oral cancer therapy in the United States is provided and takes into consideration a historical perspective; pharmacology, indications, administration, and side effect profile through an exemplar agent are illustrated; potential advantages of and challenges to integration of oral therapies are discussed; and alternative methods of patient and family education to improve compliance and outcome are discussed.
Improving medication adherence with a targeted, technology-driven disease management intervention.
TLDR
This initiative demonstrated that a targeted disease management intervention promoting patient behavior change increased the number of patients who reinitiated therapy after a period ofNonadherence and decreased the time from nonadherence to adherence.
Intentional and non-intentional non-adherence to medication amongst breast cancer patients.
...
1
2
3
4
5
...