Non-viral siRNA delivery to the lung.


SiRNAs exert their biological effect by guiding the degradation of their cognate mRNA sequence, thereby shutting down the corresponding protein production (gene silencing by RNA interference or RNAi). Due to this property, siRNAs are emerging as promising therapeutic agents for the treatment of inherited and acquired diseases, as well as research tools for… (More)


Cite this paper

@article{Thomas2007NonviralSD, title={Non-viral siRNA delivery to the lung.}, author={Mini Thomas and James J.-Q. Lu and Jianzhu Chen and Alexander M. Klibanov}, journal={Advanced drug delivery reviews}, year={2007}, volume={59 2-3}, pages={124-33} }