Non-traumatic necrosis of bone (osteonecrosis) is associated with endothelial cell activation but not thrombophilia.


OBJECTIVE The pathophysiology of non-traumatic osteonecrosis (ON) or avascular necrosis (AVN) of the femoral head remains poorly understood. Some studies have suggested the contribution of underlying thrombophilia as a mechanism; however, no specific thrombophilic factor has been consistently found in association with the disease. We are presenting data… (More)
DOI: 10.1093/rheumatology/ken206


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