Non-toxic alveolar oxygen concentration without hypoxemia during apnoeic oxygenation: an experimental study.

@article{Hstman2011NontoxicAO,
  title={Non-toxic alveolar oxygen concentration without hypoxemia during apnoeic oxygenation: an experimental study.},
  author={S H{\"o}stman and Joakim Engstr{\"o}m and F Sellgren and G{\"o}ran Hedenstierna and Anders Larsson},
  journal={Acta anaesthesiologica Scandinavica},
  year={2011},
  volume={55 9},
  pages={1078-84}
}
BACKGROUND Oxygenation without tidal breathing, i.e. apnoeic oxygenation in combination with extracorporeal carbon dioxide removal, might be an option in the treatment of acute respiratory failure. However, ventilation with 100% O₂, which is potentially toxic, is considered a prerequisite to ensure acceptable oxygenation. We hypothesized that trapping nitrogen (N₂) in the lungs before the start of apnoeic oxygenation would keep the alveolar O₂ at a non-toxic level and still maintain normoxaemia… CONTINUE READING

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 17 references

A new method for reducing the risk of oxygen toxicity in apneic oxygenation with extracorporeal CO2 removal

  • ND Nielsen, A Granfeldt, B Kjaergaard, ST Vistisen, A. Larsson
  • Intensive Care Med
  • 2009
2 Excerpts

Ventila - tion with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome

  • PP Terragni, L DelSorbo, +7 authors VM Ranieri
  • N Engl J Med
  • 2000

Similar Papers

Loading similar papers…