Non-toxic TCaPs modulate osteogenesis via differential protein and gene expression in human osteoblast cells

@inproceedings{Ibrahim2019NontoxicTM,
  title={Non-toxic TCaPs modulate osteogenesis via differential protein and gene expression in human osteoblast cells},
  author={S Ibrahim and Fazilah Fazan and Sudirman Sahid and Azman Seeni},
  year={2019}
}
Abstract In this study, the effects of a triphasic calcium phosphate bioresorbable beads (TCaPs) on biocompatibility and osteogenesis using L929 fibroblast cells and human osteoblast cells as an in vitro model have been investigated respectively and compared with the commercial MIMIX™ (CMM) and freeze dried human bone (DHB). The results showed that both materials TCaPs and CMM are non-toxic and biocompatible on L929 cells. The levels in MTT assay study of both materials are more than 70% cell… CONTINUE READING