Non-steroidal anti-inflammatory drugs. Current status and rational therapeutic use.

@article{Hart1984NonsteroidalAD,
  title={Non-steroidal anti-inflammatory drugs. Current status and rational therapeutic use.},
  author={Frank Dudley Hart and Edward C. Huskisson},
  journal={Drugs},
  year={1984},
  volume={27 3},
  pages={
          232-55
        }
}
Aspirin (acetylsalicylic acid), the first of the NSAIDs (introduced in 1899), was initially never referred to as an anti-inflammatory agent. It was the advent of cortisone in 1949 that demonstrated dramatically that corticosteroids had anti-inflammatory properties and the term 'non-steroidal anti-inflammatory drug' was first used when phenylbutazone was introduced 3 years later. Since then, the NSAIDs have proliferated. There is to date no good evidence that they halt progression of rheumatoid… CONTINUE READING

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Endoscopic evaluation of the effect of ketoprofen, ibuprofen and aspirin on the gastroduodenal mucosa

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Assessing the stable conformations of ibuprofen in solution by means of Residual Dipolar Couplings.

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