Non-steroidal anti-inflammatory drugs in domestic animals: II Disposition and clinical indications.

Abstract

Most non-steroidal anti-inflammatory drugs (NSAID's) have similar absorption and disposition characteristics. Absorption after oral administration is good, extensive plasma protein binding results in a small volume of distribution, and excretion of metabolites occurs mainly in the urine after hepatic biotransformation of the active drug. The main clinical… (More)

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