Non-selective betablocker therapy decreases intestinal permeability and serum levels of LBP and IL-6 in patients with cirrhosis.

@article{Reiberger2013NonselectiveBT,
  title={Non-selective betablocker therapy decreases intestinal permeability and serum levels of LBP and IL-6 in patients with cirrhosis.},
  author={Thomas Reiberger and Arnulf Ferlitsch and Berit Anna Payer and Mattias Mandorfer and Birgit B. Heinisch and Hubert Hayden and Frank Lammert and Michael Trauner and Markus Peck-Radosavljevic and Harald Vogelsang},
  journal={Journal of hepatology},
  year={2013},
  volume={58 5},
  pages={
          911-21
        }
}
BACKGROUND & AIMS We evaluated the gastrointestinal permeability and bacterial translocation in cirrhotic patients with portal hypertension (PHT) prior to and after non-selective betablocker (NSBB) treatment. METHODS Hepatic venous pressure gradient (HVPG) was measured prior to and under NSBB treatment. Gastroduodenal and intestinal permeability was assessed by the sucrose-lactulose-mannitol (SLM) test. Anti-gliadin and anti-endomysial antibodies were measured. Levels of LPS-binding protein… CONTINUE READING
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