Non-sedating antihistamines.

  title={Non-sedating antihistamines.},
  author={Michael A. Kaliner and William A. Check},
  journal={Allergy proceedings : the official journal of regional and state allergy societies},
  volume={9 6},
Antihistamines are effective therapy against histamine-mediated conditions, including seasonal and perennial allergic rhinitis and chronic urticaria. They may also have a therapeutic role to play in asthma. Until recently all antihistamines produced some degree of drowsiness, as well as having anticholinergic side effects. Several non-sedating antihistamines have now been developed. Evidence suggests that their freedom from central nervous system effects is due to their lack of penetration of… CONTINUE READING