Non-reward neural mechanisms in the orbitofrontal cortex.

  title={Non-reward neural mechanisms in the orbitofrontal cortex.},
  author={Edmund T. Rolls and Gustavo Deco},
  journal={Cortex; a journal devoted to the study of the nervous system and behavior},
Single neurons in the primate orbitofrontal cortex respond when an expected reward is not obtained, and behaviour must change. The human lateral orbitofrontal cortex is activated when non-reward, or loss occurs. The neuronal computation of this negative reward prediction error is fundamental for the emotional changes associated with non-reward, and with changing behaviour. Little is known about the neuronal mechanism. Here we propose a mechanism, which we formalize into a neuronal network model… CONTINUE READING
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