Non-resolving aspects of acute inflammation after spinal cord injury (SCI): indices and resolution plateau.

@article{Prss2011NonresolvingAO,
  title={Non-resolving aspects of acute inflammation after spinal cord injury (SCI): indices and resolution plateau.},
  author={Harald Pr{\"u}ss and Marcel A Kopp and Benedikt Brommer and Nicole Gatzemeier and In{\^e}s Laginha and Ulrich Dirnagl and Jan M Schwab},
  journal={Brain pathology},
  year={2011},
  volume={21 6},
  pages={652-60}
}
Inflammatory resolution is an active, highly regulated process already encoded at the onset of inflammation and required to prevent the transition into chronic inflammation associated with spreading of tissue injury and exacerbated scarring. We introduce objective, quantitative measurements [resolution indices (R(i) ) and resolution plateau (R(P) )] to characterize inflammatory resolution and to determine the persistence ("dwell time") of differential leukocyte subpopulations at the lesion site… CONTINUE READING
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